Effects of undigested protein-rich ingredients on polarised small intestinal organoid monolayers

Table 1 Overview of differentially expressed (P < 0.05) genes along with the number of related GO-biological processes in 2D organoids exposed to undigested protein sources compared to medium control (MC)

Treatment	Regulation		Differentially expressed genes ^a	GO biological processes ^b
CAS	Up	417	823	26
CAS	Down	406	823	26
SBM	Up	340	796	27
SBM	Down	456	796	27
SDPP	Up	262	379	40
SDPP	Down	117	379	40
YMW	Up	391	824	20
YMW	Down	433	824	20

Abbreviations: CAS casein, SBM soybean meal, SDPP spray dried plasma protein, YMW yellow meal worm
^aP < 0.05 and log(fold change) > |1.5|
^bAnalysed by GeneAnalytics; pathway analysis significance using a corrected P-value of < 0.05

ISSN: 2049-1891