Melatonin improves the first cleavage of parthenogenetic embryos from vitrified–warmed mouse oocytes potentially by promoting cell cycle progression

Table 2 Effect of addition (phase-wise) of melatonin on parthenogenetic development of vitrified mouse MII oocytes

Groups	NO. of oocytes activated	No. of activated oocytes developed to
Groups	NO. of oocytes activated	2-cell embryos, %	Blastocysts-1, %	Blastocysts-2, %
Control	84	79(94.40 ± 1.06)^a	65(77.39 ± 1.68)^a	65(81.97 ± 1.34)^a
Vitrification	71	59(83.10 ± 0.96)^b	37(53.02 ± 3.15)^b	37(63.76 ± 3.46)^b
Vitrification + MT	77	73(94.91 ± 0.28)^a	58(76.47 ± 0.60)^a	58(80.57 ± 0.69)^a

The numbers of 2-cell embryos and blastocyst were counted at 24 and 96 h post-activation (hpa) respectively. The rates of 2-cell embryo and blastocysts-1 were calculated from the number of activated oocytes, the rates of blastocysts-2 were calculated from the number of 2-cell embryos. The values indicate the mean ± standard error (MSE) of three independent experiments. Values with different superscripts (a, b, and c) in the same column are significantly different (P < 0.05)

ISSN: 2049-1891